Analysis of HVAC systems in COVID-19 inactivated vaccine production workshops

Through the summary of the construction experience and understanding of the relevant specifications, this paper presents the key technical points of HVAC system in the biosafety protection zone in the COVID-19 inactivated vaccine production workshop and elaborates the design details from the aspects of air supply system, exhaust system, air distribution, pressure gradient control, air conditioning auto-control system and so on. It is suggested that the standby fans should be arranged for air supply fans and exhaust fans in HVAC system of the workshop and the two-stage in-situ leak detection and filtration device should be adopted in the exhaust system in the protection zone. The directional air flow, air inlet or outlet location and other factors should be considered to meet the requirements of biological safety. Appropriate control strategies for constant and variable air volume valves should be formulated to meet the requirements of constant pressure and working condition conversion in the protection zone.